Long-term control medicines work over a longer period of time. They help to control and prevent symptoms of COPD. They take longer to work, but they may last for 12 to 24 hours. Short-acting medicines work faster, but they may last for only 4 to 6 hours. You take most of these medicines with an inhaler or a nebulizer. You take some medicines by mouth.
Always use correct inhaler and nebulizer techniques for your prescribed medicine delivery system. Refer to the information that came with your medicine from the manufacturer. Or contact your doctor if you have any questions about how to use the device, such as a metered-dose inhaler or nebulizer.
Bronchodilators
These medicines help relax the muscles around your airways so that they open up and allow more air through. There are both long-acting and short-acting bronchodilators. Here are types of long-acting bronchodilators.
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Type of medicine
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Examples
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What it does
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How it is taken
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Notes
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Beta 2-agonists
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formoterol
salmeterol
vilanterol
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Helps relax the muscles around your smaller airways so you can breathe more easily
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Inhaler or nebulizer
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There are also short-acting forms for quick relief
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Anticholinergics
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tiotropium
umeclidinium
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Helps relax the muscles around your large airways so you can breathe more easily
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Inhaler or nebulizer
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There are also short-acting forms for quick relief
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Phosphodiesterase inhibitors
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ensifentrine roflumilast
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Helps relax your airway muscles so you can breathe more easily
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Ensifentine-nebulizer Roflumilast-oral pill
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It also reduces inflammation in the airways
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Inhaled corticosteroids
These medicines help ease swelling in your airways. After using corticosteroids in your inhaler or nebulizer, gargle and rinse out your mouth with water to prevent thrush, a fungal (yeast) infection. Spit the water out. Don't swallow the water. If a mask was used, wash your face, especially around your mouth and nose, with warm water to prevent a skin rash.
Examples of these medicines are beclomethasone, budesonide, and fluticasone. They come as prefilled inhalers or as medicines taken by a nebulizer.
Combination medicines
There are also combinations of medicines that may be taken with an inhaler or a nebulizer. They may be a combination of a corticosteroid and a bronchodilator.